<p>Jannik Sinner will begin his defence of the 2025 US Open title on Wednesday (estimated match start of 02:40 AEST) when he takes on Vit Kopriva.</p> <p>No one is expecting the Czech to have a chance of winning the clash, with the Italian being extremely dominant over the last few years, especially when it comes to playing on the hardcourt surface. However, with the defending champion having only just recovered from a bout of illness, questions may be raised over his status.</p> <p>Is there any value in this betting market for bettors? Let’s take a look and see if we can find some angles to consider…</p> <h2>Sinner vs Kopriva US Open 2025 Betting Preview</h2> <p>Sinner enters the 2025 US Open as World No. 1 and defending champion, with a stunning hardcourt record (65-4 since early 2024). Despite a brief ban and a health scare pre-tournament, he remains the favourite to win the tournament as the outright winner. If he manages to have a better tournament than Carlos Alcaraz, he will retain his world number 1 status.</p> <p>Kopriva, ranked 87, has struggled at the ATP level this year, making this a likely straightforward assignment for Sinner on New York’s hard courts. He hasn’t gone beyond the second round in recent tournaments, finding it challenging on tour.</p> <p>Adding further to the Czech’s challenge is the fact that Sinner holds a 37-0 record against players outside the top 50 since 2024, making this a monumental challenge.</p> <p>Still, it will be the first time that the pair have met, which could pose some potential issues with the unknown and unexpected. Kopriva is still finding his feet on the ATP Tour, having only made his debut in 2021. He has 14 victories but has lost 22 times, with this season’s record standing at eight wins and 10 losses.</p> <p>A match against either Australian Alexei Popyrin or Finn Emil Ruusuvuori will await the winner.</p> <h2>Sinner vs Kopriva US Open 2025 Betting Predictions</h2> <p>In truth, there doesn’t appear to be too much value when looking at the latest <a href="https://www.sportsbet.com.au/betting/tennis/mens-us-open/jannik-sinner-v-vit-kopriva-9543433">Sinner vs Kopriva US Open 2025 betting odds</a>. However, Sportsbet does its best to ensure there is value across some markets for those who like to <a href="https://www.sportsbet.com.au/betting/tennis">bet on tennis </a>and are looking for something a little <a href="https://www.sportsbet.com.au/huddle/tennis/predictions/us-open-mens-singles-betting-predictions-2025">more than the outright winner</a> (Sinner in this case).</p> <p>In terms of betting value, trying to predict the ‘Correct Score 1st Set’ outcome might be an interesting&nbsp; option in this match, with Sinner expected to win the match 3-0. The ‘Jannik Sinner 6-2’ looks potentially good value, as the Italian is expected to dominate from the off and make it hard for his Czech opponent. It’s why the ‘Under’ in the ‘Total Match Games 25.5’ also appears to be worth some value, too</p>