<p>The 2025 US Open is the final Grand Slam of the season, with the world’s top players hoping to have a chance of securing victory.</p> <p>Many tennis fans will expect a Carlos Alcaraz v Jannik Sinner final. But they’ll also be hoping it’s more of a spectacle than the recent Cincinnati Open final between the pair.</p> <p>The traditional precursor to the US Open ended in a walkover for Alcaraz, with Sinner retiring 5-0 down in the first set due to illness. Now the Italian is in a race to be healthy enough to defend his 2024 US Open title.</p> <p>But can anyone else disrupt the dominance of the world numbers 1 and 2 at the USTA Billie Jean King National Tennis Center? Let’s take a look…</p> <h2>US Open 2025 Betting Preview</h2> <p>When trying to identify potential <a href="https://www.sportsbet.com.au/huddle/tennis/predictions/2025-us-open-tennis-betting-preview-odds">tennis betting opportunities for the 2025 US Open</a>, the Cincinnati Open has often been a good indicator of what to expect when the action gets underway.</p> <p>In the last two Men’s singles finals at the Cincinnati Open, the player to win that title has gone on to win the US Open. Novak Djokovic did it in 2023, while Sinner followed him last year. Could Alcaraz be about to make it a treble?</p> <p>Indeed, Alcaraz is well-liked. He won the US Open in 2022, and his record on hard courts is stellar (around 75%+ win rate over the past two years). He is a strong contender who often rises to big occasions and remains one of the hardest hitters and most physically dominant players.</p> <p>Still, he could encounter rival Sinner in the final. He has dominated hard courts this season and boasts a 12-1 hard-court record in 2025, demonstrating composure and clean ball striking. His all-around game, movement, and mental strength put him ahead as the most complete player in the draw.</p> <p>Djokovic is another who will feature heavily in the betting, albeit a little less than the aforementioned pair. Despite being 38 years old, he remains a formidable opponent, particularly with his experience and champion's mindset. He has been less consistent against the younger stars lately, which makes him an outside bet.</p> <h2>US Open 2025 Betting Predictions</h2> <p>The latest <a href="https://www.sportsbet.com.au/betting/tennis/mens-us-open/men-s-us-open-winner-2025-8552463">2025 US Open Men’s Singles betting odds</a> have already been released, with potential value possible to find across the entire market. Sinner is the slight favourite in the betting currently, sitting just ahead of Alcaraz, with Djokovic at longer odds.</p> <p>However, with the bracket yet to be determined, it could be worth keeping an eye on an each-way bet.</p> <p>Jack Draper could be worth considering, with the Brit having reached the US Open semi-finals last year. His aggressive baseline style and improved fitness suit this Slam well, making him a potential outsider.</p> <p>Daniil Medvedev is another who may intrigue each-way bettors, as the Russian is a former US Open champion. He won in 2021 and has shown that he can play on hard courts effectively. He can cause the world’s best problems with his strong serving and return game.</p>