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UEFA Champions League: Atletico Madrid vs Inter Milan Betting Predictions

25/11/2025|SB Staff|Soccer Tips & Predictions
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Atlético Madrid will host Inter Milan at the Riyadh Air Metropolitano on Thursday, November 27, at 07:00 AEDT, as both play their fifth UCL game of this year’s Group Phase.

The two teams are in contrasting forms, with it possible to argue that there is more on the line for the Spanish side than last year’s beaten finalists.

Diego Simeone’s side have had a tough four games so far, winning two and losing two. Cristian Chivu’s side have enjoyed themselves domestically in Serie A, while they’ve been perfect in the Champions League so far, winning all four of their games and doing so comprehensively.

Read on for our top Atlético Madrid vs Inter Milan betting predictions!

Atletico Madrid vs Inter Milan Betting Preview

There have been only two meetings between these sides in the UEFA Champions League, both in the 2023/24 edition of the premier soccer competition.

They met in the Round of 16, with the Spanish side emerging victorious in a penalty shootout (3-2). The first meeting ended in a 1-0 victory for the Italian sides, while Atlético produced a 2-1 home win that went to extra time and penalties.

When looking at this year’s competition, Inter have been one of the best teams so far. They’ve scored 11 goals and have conceded just one in their four games; the goal conceded came in their most recent fixture against Kairat. However, the upcoming game against Atlético is the hardest they will have faced. Atlético have had a tough run. They’ve faced Liverpool, Eintracht Frankfurt, Arsenal, and Union Saint-Gilloise. 

Lautaro Martinez is among the leaders in this year’s competition for goals scored, having netted four in three games. Marcos Llorente has three goals for Atlético in this tournament, while Marcus Thuram and Denzel Dumfries both have two each for Inter.

Both teams have enjoyed positive starts to their domestic season, adding further to the excitement of this fixture.

Atletico Madrid vs Inter Milan Betting Predictions

Given that both teams have been performing well this season, what do the Atlético Madrid vs Inter Milan betting odds suggest could happen? Sportsbet’s odds reveal that Atlético are the favourites.

Indeed, we’re predicting that Simeone’s team are victorious in this game for two reasons:

  1. The home team has won each of Atlético Madrid's last six Champions League matches.
  2. They defeated the Italians the last time they hosted them.

In addition, we predict that the ‘Yes’ in the 'Both Teams to Score' market will be selected. This has happened in each of Atlético Madrid's last six Champions League Group Stage matches at the Riyadh Air Metropolitano.

We like the value offered in the ‘Atletico Madrid 2-1’ bet outcome in the ‘Correct Score’ and think Lautaro Martinez will be good value as an ‘Anytime Goalscorer’ in this game.

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