<p>Liverpool play Atletico Madrid on Thursday, September 18, at 05:00 (AEST) at Anfield and will be aiming to go a lot further than they did last season in the UCL, after being knocked out in the Round of 16, losing on penalties to eventual winners PSG.</p> <p>Arne Slot’s side have been grinding out wins this season domestically, which could help them in Europe’s elite soccer competition. They remain unbeaten with four wins from four, but haven’t been convincing while a number of new signings bed into the club.</p> <p>This could provide Diego Simeone’s side with a chance to get a result over the Premier League champions and give Los Rojiblancos a chance to get their own UCL campaign underway in a positive way.</p> <h2>Liverpool vs Atletico Madrid Betting Preview</h2> <p>There have been six previous meetings between these two sides in the UCL, although this will be the first in this revamped format.</p> <p>Liverpool won the last two meetings, with both happening in the 2021/22 campaign. They won their Anfield encounter 2-0, having secured a 3-2 victory in Spain the previous game. However, in the 2019/20 season, they lost both encounters in the Round of 16, with Atletico Madrid going through after extra time.</p> <p>Slot will be able to call upon many of his stars as he boasts a relatively fit squad to choose from. Alexis MacAllister played against Burnley at the weekend amid doubts about his fitness, while Mohamed Salah scored a late winner from the penalty spot. We could also see a debut for Alexander Isak, after he completed his move from Newcastle. The Swedish striker didn’t feature against Burnley, and there are some question marks about when Slot will integrate Isak into the starting 11 after he missed pre-season while engineering his move to Anfield.</p> <p>Atletico have had a slow start in La Liga, winning just one of their four opening matches (two draws and a defeat), securing their first victory at the weekend against Villarreal.</p> <p>They may have former Manchester City striker Julian Alvarez available after he played 45 minutes in their most recent encounter. The Argentine was the leading scorer last season and is slowly making his return from injury. Both Jose Gimenez and Thiago Almada remain doubts, though, leaving Los Rojiblancos potentially light.</p> <h2>Liverpool vs Atletico Madrid Betting Predictions</h2> <p>In the latest <a href="https://www.sportsbet.com.au/betting/soccer/uefa-competitions/uefa-champions-league/liverpool-v-atletico-madrid-9576231">betting odds for Liverpool vs Atletico Madrid</a>, the Premier League champions are considered the favourites to take the victory.&nbsp;</p> <p>While the 'Both Teams to Score' market has failed to hit in each of Liverpool's last seven Champions League Wednesday matches against teams from Spain (in regular time only), it’s worth backing the ‘Yes’ in this one. Atletico have scored in nine of their last 11 away Champions League games, while Liverpool’s attacking style makes it likely that they’ll score at least one.</p> <p>With the 'Over 2.5 Goals' market hitting in each of Atlético Madrid's last eight Champions League league phase matches, this is also a value bet, with ‘Liverpool 2-1’ a possible correct score.</p> <p>Isak as an ‘anytime goalscorer’ could be worth a punt if he is used by Slot, as it feels written in the script.</p>