It will be the first leg of their quarter-final matchup, with the two teams clashing on Thursday, April 9, at 07:00 AEDT. 

Quick Picks

Our pick: Barcelona to win

Value bet: BTTS to hit

Long shot: Over 3.5 goals

Betting Preview

After the league action, attention will quickly change to European soccer's biggest tournament for both of these sides.

Hansi Flick's side managed to advance to this stage of the competition by dismantling Newcastle United 8-3 on aggregate.

Their home fixture (second leg) saw them record a 7-2 victory, with Raphinha and Robert Lewandowski both scoring a brace.

Diego Simeone's team also managed to defeat English Premier League opposition in the previous stage, as they overcame Tottenham Hotspur.

They had lost the second leg, but thanks to numerous errors in the first, they managed to see the tie through 7-5 on aggregate.

It's been a goal-laden tournament for both clubs, with Atletico having scored seven across the Play-Off tie against Club Brugge in addition to the 17 they scored in the Group Phase (total of 31).

Barcelona have played a tie less as they went through automatically to the Round of 16, but have managed 30 goals across the ten games played (22 in the Group Phase).

Goals can be conceded by both teams, though. Barca have shipped 17 in the competition, whereas Atletico have conceded 24.

Betting Markets to Watch

Unsurprisingly, we think there are goals in this one to be had. While neither team is goal-shy, they've also shown that they can score against each other with regularity.

Of the last 10 games played across all competitions, seven of them have had over 2.5 goals. Six of the last 10, though, saw just one team score.

In the last six meetings, four have had over 3.5 goals, which we think offers value in this match.

The BTTS is also likely to hit, as both teams have been exceptional in front of goal in this competition.

Robert Lewandowski offers value as an anytime goalscorer, as he has two goals in his six appearances against Los Rojiblancos.

The Polish striker is among the top goalscorers of all time and continues to deliver at the highest level.

Our Prediction

Check the latest Barcelona vs Atletico Madrid betting odds at Sportsbet.

Barcelona are the heavy favourites to win this encounter, and we think this is the most likely outcome.

They have been exceptionally strong at home all season, having won four of their five ties. In those, they've scored 20 goals.

Still, we think the BTTS will also offer value to hit, as it has in each of Barcelona's last 10 Champions League matches as a favourite.

Madrid aren't goal-shy, and Simeone's side will look to attack as often as they can, as they may want to take a lead to defend in the second leg.

Both clubs have been competing in La Liga at the top end of the table, which speaks to their quality and attacking prowess.

For those looking to explore soccer betting markets further, this fixture offers plenty of options beyond the match result.