<p>The first leg will take place in Spain on Thursday, April 30, with kick-off at 06:00 AEST.</p><h2>&nbsp;</h2><h2>Quick Picks</h2><p><strong>Our pick:</strong> Atletico Madrid to win</p><p><strong>Value bet:</strong> Over 2.5 goals</p><p><strong>Long shot:</strong> Havertz as an anytime goalscorer</p><h2>&nbsp;</h2><h2>Betting Preview</h2><p>In the Group Phase meeting, Arsenal managed to blow Atletico away at the Emirates, winning 4-0. Indeed, Mikel Arteta's side were rampant in that game, and continued to be that way through the Group Phase, winning each of their eight games.</p><p>However, things slowed down a little in the knockout phase. They edged past Bayer Leverkusen 3-1 on aggregate with a 2-0 home victory, needing a last-gasp goal to give them a 1-1 tie in the away leg.</p><p>Then, they only just got past Sporting in the quarter-finals, with a 1-0 aggregate win after winning the first leg 1-0 away in Portugal. Kai Havertz had scored both of the most important goals in each game to give Arsenal their place in the last four.</p><p>For Atletico, things have been a little more complicated to get to this stage of the UCL. If you want to learn <a href="https://www.sportsbet.com.au/huddle/punter-iq/guide/how-to-bet-uefa-champions-league">how to bet on the Champions League</a>, understanding the knockout format is essential.</p><p>Diego Simeone's side required the play-offs, having finished 14th after winning just four of their eight (one draw, three defeats) in the Group Phase. In the play-off, they defeated Club Brugge 7-4 on aggregate, using their home form to win 4-1.</p><p>The Round of 16 saw them face Tottenham, winning 5-2 at home before losing 3-2 in England. Los Rojiblancos still went through 7-4 once again, as they booked a place in the quarter-finals against Barcelona.</p><p>They won 3-2 on aggregate, despite losing the second leg at home 2-1. Both clubs have featured among the <a href="https://www.sportsbet.com.au/huddle/soccer/soccer-news/most-trophies-football-history">most decorated footballers</a> in European competition history.</p><h2>&nbsp;</h2><h2>Betting Markets to Watch</h2><p>When looking at the betting odds for this game, Arsenal are considered the pre-match favourites. However, we think there's <strong>value in Atletico as winners</strong>, given their home form in the competition.</p><p>Although they lost to Barcelona in the last round in front of their own fans, they've won five of their seven home ties in this year's competition. Arsenal remain unbeaten, but could be feeling fragile after some disappointing domestic results recently.</p><p>For the latest <a href="https://www.sportsbet.com.au/huddle/epl/predictions">Premier League predictions</a>, check our dedicated hub. Still, Arsenal have won each of their last seven Champions League matches against teams from Spain.</p><p><strong>Goals can offer value in this one</strong>, despite Arsenal's ability to keep clean sheets. Atletico don't appear to have too many troubles scoring their own, although their defence appears to be leaky.</p><p>We think there's value in the<strong> Over 2.5 goals</strong> in this tie, with it hitting in each of Atletico's last seven Champions League home matches.</p><h2>&nbsp;</h2><h2>Our Prediction</h2><p>Check the latest <a href="https://www.sportsbet.com.au/betting/soccer/uefa-competitions/uefa-champions-league/atletico-madrid-v-arsenal-10380180">Atletico Madrid vs Arsenal betting odds</a> at Sportsbet.</p><p>Our betting prediction is that <strong>Atletico Madrid likely win this game</strong>, as they have been pretty solid at home and Arsenal have been rocked domestically in their pursuit for silverware.</p><p>Those following <a href="https://www.sportsbet.com.au/betting/soccer/united-kingdom/english-premier-league">Premier League betting odds</a> will have noticed the Gunners' recent struggles.</p><p>Our <strong>long shot is for Kai Havertz to score anytime</strong>. As noted, he has scored important goals in this year's competition and could prove valuable for the Gunners once again.</p>