Penrith Panthers vs Wests Tigers Prediction – Round 21 2025

The purring Penrith Panthers will look to make it seven in a row when they host the Wests Tigers at CommBank Stadium on Saturday evening.

The second win of Penrith’s current streak came by an 18-14 scoreline when these sides met back in round 14. More recently, the Panthers handled the Rabbitohs 30-10 to keep their top four hopes alive.

The Tigers are unlikely to break through for a finals berth this season, but with their 21-20 win over the Titans last week, they have all but assured themselves of avoiding a fourth straight wooden spoon.

Some big inclusions at the foot of the mountains this week with Nathan Cleary, Isaah Yeo and Izack Tago all returning.

That means the Panthers will have all their stars back on deck outside of Liam Martin, who is still nursing a wrist injury.

For the Tigers, former Panther Api Koroisau is back in the 13 at hooker after coming off the bench last week, while winger Izaac Tu'itupou will make his club debut for Wests in place of another ex-Panther, Charlie Staines.

Check out our Penrith Panthers vs Wests Tigers match preview for plenty of betting tips and predictions across a host of markets. From H2H to anytime try scorer and everything in between. 

So, for all the latest news, analysis, odds, and betting tips ahead of this mouthwatering matchup, check out our Panthers vs Tigers prediction below.

 

Panthers vs Tigers Prediction and Betting Tips

 

Head-to-Head Prediction

The party Penrith have decided to throw in the second half of the season just keeps on raging after they picked up win number six on the spin last week against South Sydney.

Their opponents this week the Tigers grabbed a rare win last week, with a last gasp Adam Doueihi field goal seeing them to a dramatic 21-20 win over the Titans.

You’d imagine if the Tigers are to pull off an insane upset here, it would have to be by a similar margin to the one they won by last week.

Unfortunately for the Tigers faithful, we can’t see them even remotely getting in range of such a scoreline. A seventh straight victim loading for Penrith? We think so.

Betting tip: Penrith Panthers.

 

First Try Scorer Prediction

After being the first man on the scoresheet for his side last week, on his debut no less, we like the look of former Panther Taylan May when it comes to this market.

Players always seem to have a point to prove when coming up against their former employers and since this is the first time Taylan will take on the Panthers after their acrimonious split, he should be eager to get on the board early.

Betting tip: Taylan May.

 

Line Prediction

The Wests Tigers have failed to cover the line in eight of their last nine away matches against teams on a winning streak.

Betting tip: Penrith Panthers (-13.5).

 

Panthers vs Tigers Anytime Tryscorer Betting Tips

 

Thomas Jenkins

In each of the Wests Tigers' last seven matches at CommBank Stadium, the opposition's starting right wing has scored at least one try.

 

Tony Sukkar

In three of Penrith's last four matches, the opposition's starting right second row has scored a try.

 

Casey McLean

Casey McLean has scored at least one try in four of his last five home appearances against opponents that were ranked lower on the ladder.

 

Sunia Turuva

Sunia Turuva has scored at least one try in three of his last four appearances at CommBank Stadium.

 

Dylan Edwards

Dylan Edwards has scored at least one try in each of his last three appearances at CommBank Stadium against opponents that were ranked lower on the ladder.

 

Panthers vs Tigers Teams

 

Penrith Panthers Team List

1. Dylan Edwards 

2. Thomas Jenkins

3. Izack Tago

4. Casey McLean

5. Brian To'o

6. Blaize Talagi

7. Nathan Cleary

8. Moses Leota

9. Mitch Kenny

10. Lindsay Smith

11. Luke Garner

12. Isaiah Papalii

13. Isaah Yeo

14. Brad Schneider

15. Liam Henry

16. Luron Patea

17. Matthew Eisenhuth

 

Wests Tigers Team List

1. Sunia Turuva

2. Izaac Tu'itupou

3. Taylan May

4. Starford To'a

5. Jeral Skelton 

6. Jarome Luai

7. Latu Fainu

8. Terrell May

9. Api Koroisau

10. Alex Twal

11. Alex Seyfarth

12. Tony Sukkar

13. Adam Doueihi

14. Tristan Hope

15. Jack Bird

16. Fonua Pole

17. Sione Fainu

 

Panthers vs Tigers Match Details

 

Date: Saturday, July 26, 2025.

Kick-off: 5:30pm AEST.

Location: CommBank Stadium, Sydney.