<p>The Detroit Pistons and the Cleveland Cavaliers will take on each other at the Little Caesars Arena in Detroit on Tuesday, October 28, at 09:00 AEST.</p> <p>The two teams reacquainted themselves in preseason, with the Cavs winning that one 118-100 in Cleveland. Now, they’ll do it for real as part of the NBA regular season. Will the same outcome occur?</p> <p>The Cavs are among the leading candidates in the <a href="https://www.sportsbet.com.au/betting/basketball-us/nba-futures/nba-futures-2026-9324399">2026 NBA Championship market</a> to win the league this season, with the Pistons in middle ground.&nbsp;</p> <p>Let’s take a look at how we think things may turn out with our Detroit Pistons vs Cleveland Cavaliers betting predictions…</p> <h2>Detroit Pistons vs Cleveland Cavaliers: Betting Preview</h2> <p>When it comes to these two teams, there has been a notable trend that has occurred. In last season’s regular season, the Cavs were able to win three of the four games that were played.</p> <p>Recent history also shows the Cavaliers had a 12-game winning streak against the Pistons from March 19, 2022, to February 5, 2025. However, most recently on March 28, 2025, the Pistons defeated the Cavaliers 133-122. That was the last time they had met in the regular season.</p> <p><strong>Tim Hardaway Jr. </strong>scored 32 points in that game, but he is no longer with the team, as he joined the Denver Nuggets in the offseason. <strong>Cade Cunningham</strong> is a threat and has started the season well. He seems to enjoy the matchups against the Cavs on a personal level, as he averages around 24.8 points, 6.4 rebounds, and 9.4 assists per game.</p> <p><strong>Donovan Mitchell </strong>scored 38 points in the losing effort for the Cavs, and scored a further 17 in the preseason meeting between them. He typically gets anywhere between 20 and 45 points when these two teams meet.</p> <h2>Detroit Pistons vs Cleveland Cavaliers: Betting Predictions</h2> <p>Before making our betting prediction and looking for the best value in the Detroit Pistons vs Cleveland Cavaliers betting odds, let’s consider how the games last season finished between these two teams first:</p> <ul> <li>March 2025: Pistons 133-122 Cavaliers</li> <li>Feb 2025: Pistons 115-118 Cavs</li> <li>Jan 2025: Cavs 110-91 Pistons</li> <li>Oct 2024: Cavs 113-101 Pistons</li> </ul> <p>Our <strong>betting prediction is that the Cavs continue their winning run</strong> against the Pistons on Tuesday, as they don’t typically lose when they play. The Pistons no longer have Hardaway Jr. on their team, who excelled in the last meeting and was the key difference.</p> <p>Value could be found in backing player props. <strong>Cade Cunningham should score 20+ points</strong> in this game based on his historic averages for the Pistons against the Cavs; <strong>Donovan Mitchell could be</strong> <strong>worth value for 30+ points </strong>based on his.</p> <p>Elsewhere, it could be worth looking at the <strong>margin of victory market</strong>. A double-digit figure was common last season, and we<strong> predict 10+ points</strong> will decide this encounter once again.</p>