Week 25 has started off low scoring and somewhat unpredictable, with four more matches to come tonight and overnight.

In matches played already, Southampton held Chelsea to a draw, Everton won at Anfield for the first time since 1999 and Fulham made a move to get out of the relegation zone with a win over Sheffield United.

Overnight the pressure will be on Newcastle to keep Fulham at bay in a tough match at Manchester United.

The ‘primetime’ TV slot (11pm AEDT) sees an important London derby between West Ham and Tottenham Hotspur, which is borderline ‘must win’ for Jose Mourinho.

Two other fascinating matchups see Aston Villa hosting Leicester and Arsenal home to league leaders Manchester City.

West Ham v Tottenham, Sunday, 11pm AEDT

Huge game for both teams, with Tottenham six points behind West Ham (with a game in hand) and in the midst of a rough patch that has seen them lose four of their last five league games. The Hammers have taken a remarkable 19 of 24 possible points in their last eight EPL games…but…they have a four-game home losing streak against Spurs. And don’t forget the fact that David Moyes has never beaten Jose Mourinho.

Best Bet

Both Teams To Score Yes

West Ham v Tottenham

Aston Villa v Leicester, Monday, 1am AEDT

Third place Leicester have been in good form while eighth place Villa are up and down. Their last five include two 1-0 wins, a 0-0 draw and two bad losses (3-1 to West Ham and 3-2 to Burnley). The clubs did meet earlier in the season, with Villa stealing a late 1-0 win thanks to Ross Barkley.

Best Bet

Both Teams To Score Yes

Aston Villa v Leicester

Arsenal v Manchester City, Monday, 3:30am AEDT

City are on an incredible tear, unbeaten in 16 games and on a 12-game winning streak. Without Kevin DeBruyne and Sergio Aguero, manager Pep Guardiola has relied on his stingy defence (just 15 goals against in 24 EPL games) and a diverse group of scorers like Ilkay Gundogan, Raheem Sterling, Phil Foden etc etc. Arsenal have lost seven straight league games to City and Mikel Arteta is bound to play this one conservatively as he’s done against other top three teams.

Best Bet

Manchester City

Arsenal v Manchester City

Manchester United v Newcastle, Monday, 6am AEDT

Fulham’s win has thrust Newcastle into the relegation fight, with the Magpies just three points clear of Scott Parker’s side. They face an ominous task against United, having lost the last three at Old Trafford (aggregate score 11-5 Man Utd) and without a win there since 2013.

Best Bet

Bruno Fernandes Anytime Goalscorer

Manchester United v Newcastle